C₃₅H₃₉N₅O₄S

Base Information

• Chemical Name: C₃₅H₃₉N₅O₄S
• CAS No.: 1448552-44-0
• Molecular Formula: C₃₅H₃₉N₅O₄S
• Molecular Weight: 625.792
• Mol file: 1448552-44-0.mol

Synonyms:C₃₅H₃₉N₅O₄S

Chemical Property of C₃₅H₃₉N₅O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₃₉N₅O₄S

There total 5 articles about C₃₅H₃₉N₅O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.5%

N-[(R,R)-2-(prop-2-ynyloxyethylamino)-1,2-diphenylethyl]-4-methyl benzenesulfonamide (1448552-42-8) + ((2-azidoethoxy)methyl)benzene (66021-75-8) → C35H39N5O4S (1448552-44-0)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 30 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.tetasy.2013.05.022

Reference yield:

2-(prop-2-ynyloxy)ethanol (3973-18-0) → C35H39N5O4S (1448552-44-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 2,6-dimethylpyridine / dichloromethane / 2.25 h / 0 - 22 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0 - 5 °C / Inert atmosphere

3: sodium L-ascorbate; copper(ll) sulfate pentahydrate / tert-butyl alcohol; water / 5 h / 30 °C / Inert atmosphere

With 2,6-dimethylpyridine; copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethylamine; In dichloromethane; water; tert-butyl alcohol;

DOI:10.1016/j.tetasy.2013.05.022

Reference yield:

benzyl bromide (100-39-0) → C35H39N5O4S (1448552-44-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide; methanol / 17 h / 20 - 22 °C / Inert atmosphere

1.2: 24 h / 20 - 22 °C / Inert atmosphere

2.1: pyridine / 0 - 22 °C / Inert atmosphere

3.1: sodium azide / N,N-dimethyl-formamide / 3.5 h / 20 - 90 °C / Inert atmosphere

4.1: sodium L-ascorbate; copper(ll) sulfate pentahydrate / tert-butyl alcohol; water / 5 h / 30 °C / Inert atmosphere

With pyridine; sodium azide; copper(ll) sulfate pentahydrate; sodium hydride; sodium L-ascorbate; In methanol; water; N,N-dimethyl-formamide; mineral oil; tert-butyl alcohol;

DOI:10.1016/j.tetasy.2013.05.022

upstream raw materials:

benzyl bromide

2-Benzyloxyethanol

2-(Benzyloxy)ethyl p-toluenesulfonate

N-[(R,R)-2-(prop-2-ynyloxyethylamino)-1,2-diphenylethyl]-4-methyl benzenesulfonamide

Refernces