(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

Base Information

Chemical Name:(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone
CAS No.:1016543-77-3
Molecular Formula:C₂₁H₁₉N₅O₄S
Molecular Weight:437.479
Hs Code.:

Synonyms:(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

Suppliers and Price of (4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of (4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

There total 1 articles about (4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1016544-80-1
1-(3-(1H-1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl)-2-bromoethanone

: 17356-08-0
thiourea

: 1016543-77-3
(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

Guidance literature:: In ethanol; for 2h; Heating / reflux;

Reference yield: 32.0%

: 1016543-77-3
(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

: 75-36-5
acetyl chloride

: 1016543-87-5
N-(4-(3-(1H-1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl)thiazol-2-yl)acetamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm1002414

Reference yield: 22.9%

: 1016543-77-3
(4-(2-aminothiazole-4-yl)-2-(1H-1,2,4-triazole-1-yl)phenyl)(3,4,5-trimethoxyphenyl)methanone

: 506-96-7
Acetyl bromide

: 1016543-87-5
N-(4-(3-(1H-1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl)thiazol-2-yl)acetamide

Guidance literature:: 4-(thiazol-2-yl)-2-(3,4,5-trimethoxybenzoyl)benzoic acid; With thionyl chloride; In toluene; at 20 - 100 ℃; for 2h;

With ammonia; In tetrahydrofuran; water; at 20 ℃; for 0.5h;