ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Base Information

Chemical Name:ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside
CAS No.:399035-89-3
Molecular Formula:C₂₄H₂₆Cl₃NO₅S
Molecular Weight:546.899
Hs Code.:

Synonyms:ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Suppliers and Price of ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

There total 5 articles about ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 100-39-0
benzyl bromide

: 399035-88-2
ethyl 4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

: 399035-89-3
ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Guidance literature:: ethyl 4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside; With sodium hydride; In N,N-dimethyl-formamide; at -20 ℃; for 1h;

benzyl bromide; In N,N-dimethyl-formamide; at -15 ℃; for 1.5h;

With acetic acid; In N,N-dimethyl-formamide; at -40 - 20 ℃;
DOI:10.1016/S0008-6215(01)00213-0

Reference yield:

: C₂₀H₂₈Cl₃NO₅SSi

: 100-52-7
benzaldehyde

: 399035-89-3
ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Guidance literature:: With triethylsilane; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 5h; Inert atmosphere;
DOI:10.1002/ejoc.201101267

Reference yield:

: 1125-88-8
benzaldehyde dimethyl acetal

: 399035-89-3
ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-trichloroacetamido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1.1: (+/-)-camphor-10-sulfonic acid / dimethylformamide / 2 h / 70 °C

2.1: NaH / dimethylformamide / 1 h / -20 °C

2.2: dimethylformamide / 1.5 h / -15 °C

2.3: 91 percent / glacial AcOH / dimethylformamide / -40 - 20 °C

With camphor-10-sulfonic acid; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(01)00213-0