2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester

Base Information

• Chemical Name: 2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester
• CAS No.: 115148-06-6
• Molecular Formula: C₉H₇Cl₃O₄
• Molecular Weight: 285.511
• Mol file: 115148-06-6.mol

Synonyms:2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester

Chemical Property of 2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester

There total 1 articles about 2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

1,1,1-trichloroethanol (115-20-8) + 2,5-dihydroxybenzoic acid. (490-79-9) → 2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester (115148-06-6)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 24h; Heating;

DOI:10.1039/P19890000179

Reference yield: 89.0%

2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester (115148-06-6) → 2,2,2-trichloroethyl 2,5-dioxo-2,5-dihydrobenzoat (115148-08-8)

Guidance literature:

With manganese(IV) oxide; sodium sulfate; In dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1039/P19890000179

Reference yield:

2,5-dihydroxybenzoic acid 2,2,2-trichloroethyl ester (115148-06-6) → C30H20Cl6O8

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / Heating

2: cupric acetate monohydrate / pyridine / 40 °C

3: K₂CO₃ / acetone / Heating

With copper diacetate; potassium carbonate; In pyridine; acetone;

DOI:10.1021/ja00522a037

upstream raw materials:

1,1,1-trichloroethanol

2,5-dihydroxybenzoic acid.

Downstream raw materials:

2,2,2-trichloroethyl 2,5-dioxo-2,5-dihydrobenzoat