1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Base Information

Chemical Name:1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene
CAS No.:202813-56-7
Molecular Formula:C₃₀H₅₄O₄Si₂
Molecular Weight:534.927
Hs Code.:

Synonyms:1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Suppliers and Price of 1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

There total 4 articles about 1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 202813-70-5
8-(tert-Butyl-dimethyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-3-methylene-oct-1-en-4-ol

: 202813-56-7
1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 50 ℃; for 4h;
DOI:10.1002/anie.199728211

Reference yield:

: 73255-29-5
3-(hydroxymethyl)but-3-en-2-one

: 202813-56-7
1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / CSA / CH₂Cl₂ / 3 h / 23 °C

2: 60 percent / NaHMDS / tetrahydrofuran / 1 h / -40 °C

3: 1.) Me₃SnSnMe₃, LiCl, 2.) n-BuLi / 1.) Pd(PPh₃)4 / 1.) THF, 60 deg C, 8 h, 2.) THF, -78 deg C, 20 min; -78 to 0 deg C, 1 h

4: 94 percent / imidazole / dimethylformamide / 4 h / 50 °C

With 1H-imidazole; n-butyllithium; camphor-10-sulfonic acid; hexamethyldistannane; sodium hexamethyldisilazane; lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/anie.199728211

Reference yield:

: 202813-54-5
3-(((4-methoxybenzyl)oxy)methyl)but-3-en-2-one

: 202813-56-7
1-[4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2,3-dimethylene-octyloxymethyl]-4-methoxy-benzene

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / NaHMDS / tetrahydrofuran / 1 h / -40 °C

2: 1.) Me₃SnSnMe₃, LiCl, 2.) n-BuLi / 1.) Pd(PPh₃)4 / 1.) THF, 60 deg C, 8 h, 2.) THF, -78 deg C, 20 min; -78 to 0 deg C, 1 h

3: 94 percent / imidazole / dimethylformamide / 4 h / 50 °C

With 1H-imidazole; n-butyllithium; hexamethyldistannane; sodium hexamethyldisilazane; lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/anie.199728211