(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Base Information

Chemical Name:(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine
CAS No.:795281-92-4
Molecular Formula:C₂₇H₃₇NO₄
Molecular Weight:439.595
Hs Code.:

Synonyms:(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Suppliers and Price of (3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Chemical Property:

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

There total 2 articles about (3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 900513-88-4
(1R,2R)-2-[(R)-3-(benzyloxy)pyrrolidin-1-yl]cyclohexanol

: 867152-08-7
2-(3,4-dimethoxyphenyl)ethyl 2,2,2-trichloroethanimidate

: 795281-92-4
(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Guidance literature:: (1R,2R)-2-[(R)-3-(benzyloxy)pyrrolidin-1-yl]cyclohexanol; 2-(3,4-dimethoxyphenyl)ethyl 2,2,2-trichloroethanimidate; With tetrafluoroboric acid; In dichloromethane; at -5 - 20 ℃; for 2h;

With sodium hydroxide; In dichloromethane; water; at 0 ℃; Product distribution / selectivity;

Reference yield:

: 867152-08-7
2-(3,4-dimethoxyphenyl)ethyl 2,2,2-trichloroethanimidate

: 795281-92-4
(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

Guidance literature:: (1R,2R)-2-[(R)-3-(benzyloxy)pyrrolidin-1-yl]cyclohexanol; With tetrafluoroboric acid; In dichloromethane; at -10 - 10 ℃; for 0.25h;

2-(3,4-dimethoxyphenyl)ethyl 2,2,2-trichloroethanimidate; In dichloromethane; di-isopropyl ether; at -10 - 10 ℃; for 15 - 25h; Product distribution / selectivity;

Reference yield: 75.0%

: 795281-92-4
(3R)-3-benzyloxy-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidine

: 748810-28-8
Vernakalant hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; at 20 ℃; for 5h; under 3102.97 Torr; Product distribution / selectivity;