Technology Process of 2-ethyl-3-(3-oxomorpholin-4-yl)benzenesulfonyl chloride
There total 4 articles about 2-ethyl-3-(3-oxomorpholin-4-yl)benzenesulfonyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfuryl dichloride; acetic acid;
In
dichloromethane; water;
at 0 - 20 ℃;
for 1.58333h;
DOI:10.1021/jm4005835
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium; sulfur / tetrahydrofuran; n-heptane / 0.75 h / -78 °C / Inert atmosphere
1.2: 1.5 h / -78 °C / Inert atmosphere
2.1: potassium carbonate; copper(l) iodide; N,N,N,N,-tetramethylethylenediamine / toluene / 20 h / 110 °C / Inert atmosphere
3.1: acetic acid; sulfuryl dichloride / water; dichloromethane / 1.58 h / 0 - 20 °C
With
copper(l) iodide; n-butyllithium; sulfuryl dichloride; N,N,N,N,-tetramethylethylenediamine; potassium carbonate; sulfur; acetic acid;
In
tetrahydrofuran; n-heptane; dichloromethane; water; toluene;
DOI:10.1021/jm4005835
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate; copper(l) iodide; N,N,N,N,-tetramethylethylenediamine / toluene / 20 h / 110 °C / Inert atmosphere
2: acetic acid; sulfuryl dichloride / water; dichloromethane / 1.58 h / 0 - 20 °C
With
copper(l) iodide; sulfuryl dichloride; N,N,N,N,-tetramethylethylenediamine; potassium carbonate; acetic acid;
In
dichloromethane; water; toluene;
DOI:10.1021/jm4005835
