Technology Process of 1-benzylsulfanyl-3-bromo-2-ethylbenzene
There total 2 articles about 1-benzylsulfanyl-3-bromo-2-ethylbenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,3-dibromo-2-ethyl-benzene;
With
n-butyllithium; sulfur;
In
tetrahydrofuran; n-heptane;
at -78 ℃;
for 0.75h;
Inert atmosphere;
benzyl bromide;
In
tetrahydrofuran; n-heptane;
at -78 ℃;
for 1.5h;
Inert atmosphere;
DOI:10.1021/jm4005835
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 2.75 h / -78 - -65 °C
2.1: n-butyllithium; sulfur / tetrahydrofuran; n-heptane / 0.75 h / -78 °C / Inert atmosphere
2.2: 1.5 h / -78 °C / Inert atmosphere
With
n-butyllithium; sulfur; lithium diisopropyl amide;
In
tetrahydrofuran; n-heptane; ethylbenzene;
DOI:10.1021/jm4005835
- Guidance literature:
-
With
copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; potassium carbonate;
In
toluene;
at 110 ℃;
for 20h;
Inert atmosphere;
DOI:10.1021/jm4005835
