2-Phenyloxazole-5-carbaldehyde

Base Information

• Chemical Name: 2-Phenyloxazole-5-carbaldehyde
• CAS No.: 92629-13-5
• Molecular Formula: C10H7 N O2
• Molecular Weight: 173.171
• Hs Code.: 2934999090
• European Community (EC) Number: 851-031-9
• DSSTox Substance ID: DTXSID10534583
• Nikkaji Number: J2.612.571E
• Wikidata: Q82408490
• Mol file: 92629-13-5.mol

Synonyms:2-Phenyloxazole-5-carbaldehyde;92629-13-5;2-Phenyl-1,3-oxazole-5-carbaldehyde;2-Phenyl-oxazole-5-carbaldehyde;2-Phenyl-5-formyloxazole;SCHEMBL7450038;DTXSID10534583;ONKFKUCOEAJPJA-UHFFFAOYSA-N;AMY29048;MFCD08361771;AKOS005198454;SB39977;CS-0249241;F20865;EN300-4285597;Z1198177236

Chemical Property of 2-Phenyloxazole-5-carbaldehyde

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.589
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 43.10000
• Density: 1.216g/cm³
• LogP: 2.15410
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 173.047678466
• Heavy Atom Count: 13
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-oxazole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC=C(O2)C=O

Technology Process of 2-Phenyloxazole-5-carbaldehyde

There total 25 articles about 2-Phenyloxazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-5-(iodomethylene)-2-phenyl-4,5-dihydrooxazole (90701-94-3) → 2?phenyloxazole?5?carbaldehyde (92629-13-5)

Guidance literature:

With oxygen; In dichloromethane; at 20 ℃; for 20h; Irradiation;

DOI:10.1039/c8ob01474d

Reference yield: 94.0%

N-(prop-2-yn-1-yl)benzamide (1464-98-8) → 2?phenyloxazole?5?carbaldehyde (92629-13-5)

Guidance literature:

With diphenyl diselenide; water; Selectfluor; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1021/acscatal.8b01595

Reference yield: 91.0%

2-phenyl-5-(hydroxymethyl)oxazole (238433-75-5) → 2?phenyloxazole?5?carbaldehyde (92629-13-5)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃;

DOI:10.1016/S0040-4020(00)00019-3

upstream raw materials:

2-phenyloxazole

N,N-dimethyl-formamide

2-phenyl-5-(hydroxymethyl)oxazole

ethyl 2-phenyloxazole-5-carboxylate

Downstream raw materials:

(E)-3-(2-phenyloxazol-5-yl)propenoic acid

diethyl 2-(2-phenyloxazol-5-yl)methylenemalonate

amide of 2-phenyloxazole-5-carboxylic acid

methyl 2-phenyl-1,3-oxazole-5-carboxylate