1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester

Base Information

Chemical Name:1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester
CAS No.:92501-46-7
Molecular Formula:C₁₄H₁₉NO₃
Molecular Weight:249.31
Hs Code.:
Mol file:92501-46-7.mol

Synonyms:Ethyl2-(6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate

Suppliers and Price of 1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester

Chemical Property:

PSA：47.56000
LogP:2.16400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester

There total 7 articles about 1-Isoquinolineacetic acid,1,2,3,4-tetrahydro-6-methoxy-,ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: C₁₄H₁₇NO₃

: 92501-46-7
(6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid ethyl ester

Guidance literature:: With platinum(IV) oxide; hydrogen; In acetic acid; at 20 ℃; for 3h;

Reference yield:

: 96077-49-5
1-carbethoxymethylene-6-methoxy-1,2,3,4-tetrahydroisoquinoline

: 92501-46-7
(6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid ethyl ester

Guidance literature:: With hydrogen; acetic acid; platinum(IV) oxide; at 20 ℃; for 3h;
DOI:10.1016/S0968-0896(03)00452-8

Reference yield:

: 2039-67-0
2-(3-methoxyphenyl)-1-ethanamine

: 92501-46-7
(6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 63 percent / K₂CO₃ / CH₂Cl₂ / 0.5 h / 0 °C

2: 7.56 g / POCl₃ / 4 h / 80 °C

3: 4.88 g / H₂; acetic acid / PtO₂ / 3 h / 20 °C

With hydrogen; potassium carbonate; acetic acid; trichlorophosphate; platinum(IV) oxide; In dichloromethane; 2: Bischler-Napieralski reaction;
DOI:10.1016/S0968-0896(03)00452-8