(2S,3S)-(+)-erythro-3-phenyl-2-pentanol

Base Information

• Chemical Name: (2S,3S)-(+)-erythro-3-phenyl-2-pentanol
• CAS No.: 74365-67-6
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.247
• Mol file: 74365-67-6.mol

Synonyms:(2S,3S)-(+)-erythro-3-phenyl-2-pentanol

Chemical Property of (2S,3S)-(+)-erythro-3-phenyl-2-pentanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-(+)-erythro-3-phenyl-2-pentanol

There total 40 articles about (2S,3S)-(+)-erythro-3-phenyl-2-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(E)-(1-ethylpropenyl)benzene (4165-86-0) → threo-3-phenylpentan-2-ol (4564-82-3,6932-54-3,6932-55-4,74365-66-5,74365-67-6,97414-77-2,97414-78-3)

Guidance literature:

(E)-(1-ethylpropenyl)benzene; With dimethylsulfide borane complex; In diethyl ether; at 0 - 20 ℃; for 2h;

With dihydrogen peroxide; sodium hydroxide; In water; at 0 - 20 ℃; for 4h;

DOI:10.1002/anie.201703340

Reference yield: 75.0%

(Z)-(1-ethylpropenyl)benzene (4165-78-0) → erythro-3-phenylpentan-2-ol (4564-82-3,6932-54-3,6932-55-4,74365-66-5,74365-67-6,97414-77-2,97414-78-3)

Guidance literature:

(Z)-(1-ethylpropenyl)benzene; With dimethylsulfide borane complex; In diethyl ether; at 0 - 20 ℃; for 2h;

With dihydrogen peroxide; sodium hydroxide; In water; at 0 - 20 ℃; for 4h;

DOI:10.1002/anie.201703340

Reference yield:

(1-ethylpropyl)benzene (1196-58-3) → 1-Phenyl-1-propanol (93-54-9) + 3-phenylpentan-3-ol (1565-71-5) + (+/-)-3-phenylpentan-1-ol (2845-28-5,2845-25-2,91967-84-9) + erythro-3-phenylpentan-2-ol (4564-82-3,6932-54-3,6932-55-4,74365-66-5,74365-67-6,97414-77-2,97414-78-3) + threo-3-phenylpentan-2-ol (4564-82-3,6932-54-3,6932-55-4,74365-66-5,74365-67-6,97414-77-2,97414-78-3)

Guidance literature:

With lithium aluminium tetrahydride; Perbenzoic acid; Mechanism; Product distribution; 2.) ether, 30 min, reflux; study of the regioselectivity of autoxidation by reduction of the corresponding oxidation-mixture;

upstream raw materials:

(Z)-(1-ethylpropenyl)benzene

(2RS)-2-phenylbutanal

1-phenyl-acetone

3-phenyl-2-pentanone