2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

Base Information

Chemical Name:2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester
CAS No.:1007873-98-4
Molecular Formula:C₁₃H₁₃NO₂S
Molecular Weight:247.318
Hs Code.:
DSSTox Substance ID:DTXSID801202786

Synonyms:2-methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester;1007873-98-4;methyl 2-methyl-5-m-tolylthiazole-4-carboxylate;SCHEMBL270026;NQIAJWCHXLSJNG-UHFFFAOYSA-N;DTXSID801202786;AKOS005210985;Methyl 2-methyl-5-(3-methylphenyl)-4-thiazolecarboxylate

Suppliers and Price of 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:247.06669983
Heavy Atom Count:17
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C2=C(N=C(S2)C)C(=O)OC

Technology Process of 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

There total 3 articles about 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 955961-34-9
3-chloro-2-oxo-3-m-tolylpropionic acid methylester

: 62-55-5
thioacetamide

: 1007873-98-4
2-methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

Guidance literature:: In acetonitrile; for 5h; Molecular sieve;

Reference yield:

: 620-23-5
m-tolyl aldehyde

: 1007873-98-4
2-methyl-5-m-tolyl-thiazole-4-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / -60 - 20 °C

2: acetonitrile / Molecular sieve

With potassium tert-butylate; In tetrahydrofuran; acetonitrile;