(S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine

Base Information

• Chemical Name: (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine
• CAS No.: 102817-14-1
• Molecular Formula: C₁₈H₂₁NO₃S₂
• Molecular Weight: 363.502
• Mol file: 102817-14-1.mol

Synonyms:(S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine

Chemical Property of (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine

There total 1 articles about (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-(SS)-S-methyl-S-phenyl-N-(p-tolylsulphonyl)sulphoximine (42153-74-2,49620-56-6,104527-65-3,91933-71-0) + isobutyraldehyde (78-84-2) → C18H21NO3S2 (102817-20-9) + (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine (102817-14-1)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)98734-3

Reference yield:

(S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine (102817-14-1) → (2R)-2,3-Dimethylbutanoic acid (14287-61-7,15071-34-8,22160-11-8,27855-05-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) MeLi / tetrahydrofuran; diethyl ether / 1.) -78 deg C, 30 min, 2.) -78 deg C, 20 min.

2: tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) r.t., 30 min

3: 30percent H₂O₂ / 1 h

With methyllithium; dihydrogen peroxide; In tetrahydrofuran; diethyl ether;

DOI:10.1039/p19960001673

Reference yield:

(S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine (102817-14-1) → C28H37NO3S2SeSi

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) MeLi / tetrahydrofuran; diethyl ether / 1.) -78 deg C, 30 min, 2.) -78 deg C, 20 min.

2: tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) r.t., 30 min

With methyllithium; In tetrahydrofuran; diethyl ether;

DOI:10.1039/p19960001673

upstream raw materials:

(+)-(S_S)-S-methyl-S-phenyl-N-(p-tolylsulphonyl)sulphoximine

isobutyraldehyde

Downstream raw materials:

(R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine

(2R)-2,3-Dimethylbutanoic acid

(2S)-2,3-Dimethylbutanoic acid