4-phenyl-2,6-heptandione

Base Information

• Chemical Name: 4-phenyl-2,6-heptandione
• CAS No.: 235085-09-3
• Molecular Formula: C₁₃H₁₄O
• Molecular Weight: 186.254
• Mol file: 235085-09-3.mol

Synonyms:4-phenyl-2,6-heptandione

Chemical Property of 4-phenyl-2,6-heptandione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-phenyl-2,6-heptandione

There total 2 articles about 4-phenyl-2,6-heptandione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-phenylheptane-2,6-dione (75359-71-6) → 4-phenyl-2,6-heptandione (235085-09-3)

Guidance literature:

With 9-epi-9-amino-9-deoxyquinine; acetic acid; In toluene; at -15 ℃; for 48 - 96h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.200802497

Reference yield:

acetone (67-64-1) + 1-Phenylbut-1-en-3-one (122-57-6) → 4-phenyl-2,6-heptandione (235085-09-3) + (5R)-3-methyl-5-phenylcyclohex-2-enone

Guidance literature:

With C₁₆H₂₄N₂O₄; In 5,5-dimethyl-1,3-cyclohexadiene; at 30 ℃; for 96h; Overall yield = 80 %; enantioselective reaction;

DOI:10.1016/j.tet.2017.01.004

Reference yield:

4-phenyl-2,6-heptandione (235085-09-3) → anti-(2S,3S,5S)-2,3-epoxy-3-methyl-5-phenylcyclohexanone (1431136-81-0)

Guidance literature:

With 9-amino(9-deoxy)epiquinidine di(trifluoroacetic acid); dihydrogen peroxide; In 1,4-dioxane; water; at 50 ℃; for 48h; enantioselective reaction;

DOI:10.1021/ja402058v

upstream raw materials:

4-phenylheptane-2,6-dione

acetone

1-Phenylbut-1-en-3-one

Downstream raw materials:

anti-(2S,3S,5S)-2,3-epoxy-3-methyl-5-phenylcyclohexanone