(4-BROMO-3,5-DIMETHYL)PHENYL BENZYL ETHER

Base Information

• Chemical Name: (4-BROMO-3,5-DIMETHYL)PHENYL BENZYL ETHER
• CAS No.: 95741-44-9
• Molecular Formula: C15H15 Br O
• Molecular Weight: 291.187
• Hs Code.: 2909309090
• Mol file: 95741-44-9.mol

Synonyms:Ether,benzyl 4-bromo-3,5-xylyl (6CI); 3,5-Dimethyl-4-bromo-1-(benzyloxy)benzene

Chemical Property of (4-BROMO-3,5-DIMETHYL)PHENYL BENZYL ETHER

Chemical Property:

• Melting Point: 44-49 °C (methanol)
• PSA: 9.23000
• LogP: 4.64490

Purity/Quality:

(4-Bromo-3,5-dimethyl)phenylbenzylether 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-BROMO-3,5-DIMETHYL)PHENYL BENZYL ETHER

There total 2 articles about (4-BROMO-3,5-DIMETHYL)PHENYL BENZYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-bromo-3,5-dimethylphenol (7463-51-6) + benzyl chloride (100-44-7) → 1-((4-bromo-3,5-dimethylphenoxy)methyl)benzene (95741-44-9)

Guidance literature:

4-bromo-3,5-dimethylphenol; With sodium hydroxide; In methanol; at 0 ℃; for 2h;

benzyl chloride; In 1,2-dimethoxyethane; at 35 ℃; for 24h;

DOI:10.1016/S0957-4166(00)00250-0

Reference yield: 97.0%

4-bromo-3,5-dimethylphenol (7463-51-6) + benzyl bromide (100-39-0) → 1-((4-bromo-3,5-dimethylphenoxy)methyl)benzene (95741-44-9)

Guidance literature:

4-bromo-3,5-dimethylphenol; benzyl bromide; With potassium carbonate; In acetonitrile; at 20 ℃; for 16h;

With hydrogenchloride; In water; acetonitrile;

Reference yield: 95.0%

di-tert-butyl dicarbonate (24424-99-5) + 1-((4-bromo-3,5-dimethylphenoxy)methyl)benzene (95741-44-9) → tert-butyl 4-(benzyloxy)-2,6-dimethylbenzoate (1361198-52-8)

Guidance literature:

1-((4-bromo-3,5-dimethylphenoxy)methyl)benzene; With n-butyllithium; In N,N-dimethyl-formamide; at -78 ℃; for 0.5h; Inert atmosphere;

di-tert-butyl dicarbonate; In N,N-dimethyl-formamide; at -78 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/anie.201206370

upstream raw materials:

4-bromo-3,5-dimethylphenol

benzyl chloride

benzyl bromide

Downstream raw materials:

2,6-dimethyl-4-hydroxybenzoic acid

4-(benzyloxy)-2,6-dimethylbenzaldehyde

4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylbenzaldehyde

[4-(2,6-dimethyl-4-vinylbenzyl)-2-isopropylphenoxy]triisopropylsilane