phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone

Base Information

• Chemical Name: phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone
• CAS No.: 1374451-50-9
• Molecular Formula: C₂₄H₁₇NO
• Molecular Weight: 335.405
• Mol file: 1374451-50-9.mol

Synonyms:phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone

Chemical Property of phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone

There total 6 articles about phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-(4-phenylphenyl)pyridine (93324-66-4) + toluene (108-88-3,15644-74-3,16713-13-6) → phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone (1374451-50-9)

Guidance literature:

With N-hydroxyphthalimide; oxygen; palladium diacetate; at 80 ℃; for 24h; under 760.051 Torr;

DOI:10.1021/cs502126n

Reference yield: 75.0%

2-(4-phenylphenyl)pyridine (93324-66-4) + N,N-phenyl-p-toluenesulfonylbenzamide (74542-54-4) → phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone (1374451-50-9)

Guidance literature:

With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; 2,4,6-triisopropylbenzoic acid; potassium carbonate; Tri(p-tolyl)phosphine; In acetone; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.1c00464

Reference yield: 70.0%

2-(4-phenylphenyl)pyridine (93324-66-4) + benzil (134-81-6) → phenyl(4-(pyridin-2-yl)-[1,1'-biphenyl]-3-yl)methanone (1374451-50-9)

Guidance literature:

With tert.-butylhydroperoxide; palladium diacetate; In tetrahydrofuran; at 100 ℃; for 12h;

DOI:10.1021/ol3020557

upstream raw materials:

2-(4-phenylphenyl)pyridine

benzil

2-bromo-pyridine

4-biphenylboronic acid

Downstream raw materials:

2-([1,1':3',1''-terphenyl]-4'-yl)pyridine