N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

Base Information

Chemical Name:N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide
CAS No.:132312-45-9
Molecular Formula:C₁₉H₁₇ClN₄O₂
Molecular Weight:368.823
Hs Code.:

Synonyms:N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

Chemical Property:

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Technology Process of N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

There total 3 articles about N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 132312-86-8
2-Chloro-N-(2'-chloro-3'-pyridinyl)-3-pyridinecarboxamide

: 2393-23-9
4-methoxy-benzylamine

: 132312-45-9
N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

Guidance literature:: In xylene; for 2h; Heating;
DOI:10.1021/jm00111a045

Reference yield:

: 6298-19-7
2-chloro-3-aminopyridine

: 132312-45-9
N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / pyridine / cyclohexane; dioxane / Ambient temperature

2: 91 percent / xylene / 2 h / Heating

With pyridine; In 1,4-dioxane; cyclohexane; xylene;
DOI:10.1021/jm00111a045

Reference yield:

: 49609-84-9
2-Chloronicotinoyl chloride

: 132312-45-9
N-(2-chloro-3-pyridinyl)-2-<<(4-methoxyphenyl)methyl>amino>-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / pyridine / cyclohexane; dioxane / Ambient temperature

2: 91 percent / xylene / 2 h / Heating

With pyridine; In 1,4-dioxane; cyclohexane; xylene;
DOI:10.1021/jm00111a045