BZL-D-ALA-OME HCL

Base Information

• Chemical Name: BZL-D-ALA-OME HCL
• CAS No.: 95071-12-8
• Molecular Formula: C₁₁H₁₅NO₂*ClH
• Molecular Weight: 229.707
• Hs Code.: 2922499990
• Mol file: 95071-12-8.mol

Synonyms:N-Benzyl-D-alaninemethyl ester hydrochloride

Chemical Property of BZL-D-ALA-OME HCL

Chemical Property:

• PSA: 38.33000
• LogP: 2.92070

Purity/Quality:

98%Min ^*data from raw suppliers

Methyl (3R)-3-(benzylamino)butanoate hydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BZL-D-ALA-OME HCL

There total 5 articles about BZL-D-ALA-OME HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + (-)-N-benzyl-(R)-Ala (65491-01-2) → (R)-N-benzyl-1-methoxy-1-oxopropan-2-aminium chloride (95071-12-8)

Guidance literature:

With hydrogenchloride; for 12h;

DOI:10.1021/ja00293a038

Reference yield:

2-(benzylidene-amino)-propionic acid methyl ester (53933-42-9,112674-72-3,120328-90-7,40216-71-5) → (S)-N-benzyl-1-methoxy-1-oxopropan-2-aminium chloride (95071-12-8)

Guidance literature:

2-(benzylidene-amino)-propionic acid methyl ester; With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

With hydrogenchloride; In diethyl ether; at 0 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1039/c4cc03660c

Reference yield:

(R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propionic acid methyl ester (112674-72-3) → (R)-N-benzyl-1-methoxy-1-oxopropan-2-aminium chloride (95071-12-8)

Guidance literature:

(R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propionic acid methyl ester; With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

With hydrogenchloride; In diethyl ether; at 0 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1039/c4cc03660c

upstream raw materials:

methanol

(-)-N-benzyl-(R)-Ala

benzaldehyde

(R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propionic acid methyl ester

Downstream raw materials:

C₂₀H₂₉N₃O₅

tert-butyl (S)-2-allyl-2-(benzyl(1-methoxy-1-oxopropan-2-yl)carbamoyl)hydrazine-1-carboxylate

tert-butyl (S)-2-(benzyl(1-methoxy-1-oxopropan-2-yl)carbamoyl)-2-(but-3-en-1-yl)hydrazine-1-carboxylate

(2S,5S)-2,5-dimethyl-1-(phenylmethyl)piperazine hydrochloride