2,2'-diquinolyl ether

Base Information

• Chemical Name: 2,2'-diquinolyl ether
• CAS No.: 74857-04-8
• Molecular Formula: C₁₈H₁₂N₂O
• Molecular Weight: 272.306
• Mol file: 74857-04-8.mol

Synonyms:2,2'-diquinolyl ether

Chemical Property of 2,2'-diquinolyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-diquinolyl ether

There total 6 articles about 2,2'-diquinolyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

Quinoline N-oxide (1613-37-2) + p-toluenesulfonyl chloride (98-59-9) → N-(2-quinolyl)-2-quinolone (10168-37-3) + 2,2'-diquinolyl ether (74857-04-8) + quinolin-2-yl 4-methylbenzenesulfonate (74857-16-2) + 2-quinolone (59-31-4,70254-42-1,493-62-9)

Guidance literature:

With triethylamine; In chloroform; water; for 12h; Product distribution; Mechanism; Ambient temperature; other solvents;

DOI:10.1248/cpb.28.424

Reference yield: 35.0%

Quinoline N-oxide (1613-37-2) → N-(2-quinolyl)-2-quinolone (10168-37-3) + 2,2'-diquinolyl ether (74857-04-8) + quinolin-2-yl 4-methylbenzenesulfonate (74857-16-2) + 2-quinolone (59-31-4,70254-42-1,493-62-9)

Guidance literature:

With triethylamine; p-toluenesulfonyl chloride; In chloroform; water; for 12h; Ambient temperature;

DOI:10.1248/cpb.28.424

Reference yield: 23.0%

Quinoline N-oxide (1613-37-2) → N-(2-quinolyl)-2-quinolone (10168-37-3) + 2,2'-diquinolyl ether (74857-04-8) + 2-quinolone (59-31-4,70254-42-1,493-62-9)

Guidance literature:

With triethylamine; p-toluenesulfonyl chloride; In water; acetone; for 12h; Ambient temperature;

DOI:10.1248/cpb.28.424

upstream raw materials:

Quinoline N-oxide

p-toluenesulfonyl chloride

2,2'-oxybis(4-chloroquinoline)

{Cu(μ-O2CC6H5)(NC9H7)2}2

Downstream raw materials:

2-bromoquinoline

2-quinolone

2-(2,4,6-trimethylphenyl)quinoline