5-Phenylisoxazole-3-carbohydrazide

Base Information

Chemical Name:5-Phenylisoxazole-3-carbohydrazide
CAS No.:90946-22-8
Molecular Formula:C10H9 N3 O2
Molecular Weight:203.2
Hs Code.:2934999090
European Community (EC) Number:623-096-1
DSSTox Substance ID:DTXSID90429428
Wikidata:Q82242460
Mol file:90946-22-8.mol

Synonyms:5-phenylisoxazole-3-carbohydrazide;90946-22-8;5-phenyl-1,2-oxazole-3-carbohydrazide;5-Phenylisoxazole-3-carboxylic acid hydrazide;SCHEMBL18593297;DTXSID90429428;MFCD06199333;AKOS001224143;5-Phenylisoxazole-3-carboxylic acid hyd&;CS-0241981;EN300-24258;5-Phenylisoxazole-3-carboxylic acid hydrazide, 97%;Z164731656

Suppliers and Price of 5-Phenylisoxazole-3-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Phenylisoxazole-3-Carbohydrazide
50mg
$ 45.00

Sigma-Aldrich
5-Phenylisoxazole-3-carboxylic acid hydrazide 97%
1g
$ 91.00

Sigma-Aldrich
5-Phenylisoxazole-3-carboxylic acid hydrazide 97%
5g
$ 386.00

Crysdot
5-Phenylisoxazole-3-carbohydrazide 97%
5g
$ 564.00

American Custom Chemicals Corporation
5-PHENYLISOXAZOLE-3-CARBOHYDRAZIDE 95.00%
1G
$ 202.65

American Custom Chemicals Corporation
5-PHENYLISOXAZOLE-3-CARBOHYDRAZIDE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
5-PHENYLISOXAZOLE-3-CARBOHYDRAZIDE 95.00%
2.5G
$ 932.60

AK Scientific
5-Phenylisoxazole-3-carbohydrazide
5g
$ 482.00

AK Scientific
5-Phenylisoxazole-3-carbohydrazide
10g
$ 833.00

Abosyn
5-phenylisoxazole-3-carbohydrazide 95%-98%
1g
$ 750.00

Total 7 raw suppliers

Chemical Property of 5-Phenylisoxazole-3-carbohydrazide

Chemical Property:

Melting Point:149-153 °C(lit.)
Refractive Index:1.595
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：81.15000
Density:1.284g/cm³
LogP:2.03630
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:203.069476538
Heavy Atom Count:15
Complexity:229

Purity/Quality:

99% ^*data from raw suppliers

5-Phenylisoxazole-3-Carbohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=NO2)C(=O)NN

Technology Process of 5-Phenylisoxazole-3-carbohydrazide

There total 3 articles about 5-Phenylisoxazole-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 7063-99-2
ethyl 5-phenylisoxazole-3-carboxylate

: 90946-22-8
5-phenylisoxazole-3-carboxylic acid hydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 4h; Reflux;
DOI:10.1016/j.bioorg.2021.105334

Reference yield:

: 98-86-2
acetophenone

: 90946-22-8
5-phenylisoxazole-3-carboxylic acid hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium / methanol / 1 h / 0 - 10 °C

2: hydroxylamine hydrochloride / methanol / Reflux

3: hydrazine hydrate / methanol / Reflux

With hydroxylamine hydrochloride; sodium; hydrazine hydrate; In methanol;
DOI:10.1007/s00044-019-02388-4

Reference yield:

: 6296-54-4
ethyl 2,4-dioxo-4-phenylbutyrate

: 90946-22-8
5-phenylisoxazole-3-carboxylic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux

2: hydrazine hydrate / ethanol / Reflux

With hydrazine hydrate; hydroxylamine hydrochloride; In ethanol;