1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl

Base Information

• Chemical Name: 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl
• CAS No.: 81926-14-9
• Molecular Formula: C₁₄H₂₆N₂O₂*2I
• Molecular Weight: 508.182
• Mol file: 81926-14-9.mol

Synonyms:1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl

Chemical Property of 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl

There total 2 articles about 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,4-dihydroxy-2,5-di-(dimethylaminomethyl)phenyl (6339-48-6) + methyl iodide (74-88-4) → 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl (81926-14-9)

Guidance literature:

In dichloromethane; for 24h; Ambient temperature;

Reference yield:

hydroquinone (123-31-9,8027-02-9) → 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl (81926-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 1 h / Heating

1.2: 13 percent / aq. HCl / tetrahydrofuran / 2 h / Heating

2.1: 71 percent / acetonitrile

In tetrahydrofuran; acetonitrile;

DOI:10.1016/j.bmcl.2005.12.007

Reference yield: 27.0%

trimethylsulfoxonium iodide (1774-47-6) + 1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl (81926-14-9) → 4,10-dioxatricyclo[7.3.0.03,7]dodeca-1,3(7),8-triene (81926-24-1)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; 1.) room temperature, 1.5 h, 2.) 60 deg C, 4 h;

upstream raw materials:

1,4-dihydroxy-2,5-di-(dimethylaminomethyl)phenyl

methyl iodide

hydroquinone

Downstream raw materials:

4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene