Hydroquinone, 2,5-bis((dimethylamino)methyl)-

Base Information

• Chemical Name: Hydroquinone, 2,5-bis((dimethylamino)methyl)-
• CAS No.: 6339-48-6
• Molecular Formula: C12H20N2O2
• Molecular Weight: 224.303
• NSC Number: 43303,38360,30187
• UNII: 7B4L97Q8XI
• DSSTox Substance ID: DTXSID30212795
• Nikkaji Number: J1.498.787H
• Wikidata: Q83087999
• ChEMBL ID: CHEMBL1565767
• Mol file: 6339-48-6.mol

Synonyms:6339-48-6;Hydroquinone, 2,5-bis((dimethylamino)methyl)-;2,5-bis[(dimethylamino)methyl]benzene-1,4-diol;2,5-Bis((dimethylamino)methyl)hydroquinone;2,5-di[(dimethylamino)methyl]benzene-1,4-diol;NSC 38360;BRN 2807834;2,5-bis[(dimethylamino)methyl]hydroquinone;MLS000849812;7B4L97Q8XI;2,5-Bis((dimethylamino)methyl)-1,4-benzenediol;NSC38360;NSC-30187;NSC-38360;NSC-43303;SMR000455830;Xylohydroquinone, alpha(sup 2),alpha(sup 5)-bis(dimethylamino)-;4-13-00-02668 (Beilstein Handbook Reference);NSC30187;Maybridge1_002097;2,5-bis(dimethylaminomethyl)benzene-1,4-diol;UNII-7B4L97Q8XI;Oprea1_318263;cid_95699;CHEMBL1565767;SCHEMBL11127980;BDBM52931;HMS547H07;DTXSID30212795;HMS2790C13;NSC43303;CCG-233785;NCGC00246661-01;LS-77290;2,5-bis[(dimethylamino)methyl]-hydroquinone;1,4-BENZENEDIOL, 2,5-BIS((DIMETHYLAMINO)METHYL)-

Chemical Property of Hydroquinone, 2,5-bis((dimethylamino)methyl)-

Chemical Property:

• Vapor Pressure: 4.72E-05mmHg at 25°C
• Boiling Point: 339.3°Cat760mmHg
• Flash Point: 156.3°C
• Density: 1.124g/cm³
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 224.152477885
• Heavy Atom Count: 16
• Complexity: 187

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)CC1=CC(=C(C=C1O)CN(C)C)O

Technology Process of Hydroquinone, 2,5-bis((dimethylamino)methyl)-

There total 6 articles about Hydroquinone, 2,5-bis((dimethylamino)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + dimethyl amine (124-40-3) + hydroquinone (123-31-9,8027-02-9) → 1,4-dihydroxy-2,5-di-(dimethylaminomethyl)phenyl (6339-48-6)

Guidance literature:

In water; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2018.11.040

Reference yield:

hydroquinone (123-31-9,8027-02-9) → 1,4-dihydroxy-2,5-di-(dimethylaminomethyl)phenyl (6339-48-6)

Guidance literature:

Multi-step reaction with 2 steps

1: dioxane

2: water

With 1,4-dioxane; water;

DOI:10.1021/ja01166a094

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + formic acid (64-18-6) + 3,8-dimethyl-2,3,4,7,8,9-hexahydro-benzo[1,2-e;4,5-e']bis[1,3]oxazine (73698-54-1) → 1,4-dihydroxy-2,5-di-(dimethylaminomethyl)phenyl (6339-48-6)

Guidance literature:

With water;

DOI:10.1021/ja01166a094

upstream raw materials:

formaldehyd

formic acid

3,8-dimethyl-2,3,4,7,8,9-hexahydro-benzo[1,2-e;4,5-e']bis[1,3]oxazine

dimethyl amine

Downstream raw materials:

2,5-dimethylhydroquinone

2,5-bis-[(dimethyl-oxy-amino)-methyl]-hydroquinone

1,4-dihydroxy-2,5-di-(trimethylammonium iodide-methyl)phenyl

4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene