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2,5-bis[(dimethylamino)methyl]benzene-1,4-diol, also known as 2,5-bis(dimethylaminomethyl)benzene-1,4-diol, is an organic compound with the molecular formula C12H20N2O2. It is a colorless, crystalline solid that is soluble in water and various organic solvents. 2,5-bis[(dimethylamino)methyl]benzene-1,4-diol is characterized by its two dimethylamino groups attached to the methylene carbons of a benzene ring, with a 1,4-diol functional group present on the benzene ring. It is used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its amine and hydroxyl functional groups, it can participate in a range of chemical reactions, such as condensation, substitution, and addition reactions, making it a versatile building block in organic synthesis.

6339-48-6

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6339-48-6 Usage

Structure

Symmetrical diol derived from benzene with two dimethylamino-methyl substituents on the 2 and 5 positions

Common uses

Reagent in organic synthesis, forms stable complexes with transition metal ions, fluorescent probe for detecting proteins and nucleic acids in biological samples, potential applications in photonic devices and pH sensors

Health risks

May pose health risks if not properly handled

Check Digit Verification of cas no

The CAS Registry Mumber 6339-48-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6339-48:
(6*6)+(5*3)+(4*3)+(3*9)+(2*4)+(1*8)=106
106 % 10 = 6
So 6339-48-6 is a valid CAS Registry Number.

6339-48-6Relevant academic research and scientific papers

A thiol-inducible and quick-response DNA cross-linking agent

Xu, Yuanzhen,Wei, Hongbo,Chen, Jianjun,Gao, Kun

supporting information, p. 281 - 283 (2018/11/27)

Three new 2,4-dinitrobenzenesulfonyl derivatives 1–3 were successfully prepared for the first time using a simple process. They were efficiently triggered by thiols (glutathione and L-cysteine) to release the corresponding phenol derivatives (4–6) within

Biological studies of photoinducible phenol quaternary ammonium derivatives

Song, Yang,Wang, Ping,Wu, Juanjuan,Zhou, Xiang,Zhang, Xiao-Lian,Weng, Linhong,Cao, Xiaoping,Liang, Feng

, p. 1660 - 1664 (2007/10/03)

Three water-soluble DNA cross-linking phenol quaternary ammonium derivatives 3, 4, and 5 could inhibit the transcription in vitro by photoactivation. DNA interstrand cross-linking action might be the key factor to inhibit transcription by these compounds.

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