5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Base Information

Chemical Name:5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt
CAS No.:1073186-85-2
Molecular Formula:C₇H₁₇NO₅*C₂₅H₃₆N₂O₅S₂
Molecular Weight:703.919
Hs Code.:

Synonyms:5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Suppliers and Price of 5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

There total 8 articles about 5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1073186-72-7
5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid

: 6284-40-8,97780-33-1
1-deoxy-1-(methylamino)-D-glucitol

: 1073186-85-2
5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Guidance literature:: In tetrahydrofuran; water; at 20 ℃; for 0.5h;

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 1073186-85-2
5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine / dichloromethane / 16.75 h / 0 - 20 °C

2.1: caesium carbonate / butanone / 8 h / 60 °C

2.2: 16.5 h / 20 °C

2.3: 0.5 h

3.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 5 h / 20 °C

4.1: methanol; lithium hydroxide; water / tetrahydrofuran / 3 h / 20 °C

4.2: pH 2

5.1: tetrahydrofuran; water / 0.5 h / 20 °C

With methanol; lithium hydroxide; water; caesium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water; butanone;

Reference yield:

: 141699-59-4
1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate

: 1073186-85-2
5-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-1-methyl-1H-pyrrole-2-carboxylic acid meglumine salt

Guidance literature:: Multi-step reaction with 4 steps

1.1: caesium carbonate / butanone / 8 h / 60 °C

1.2: 16.5 h / 20 °C

1.3: 0.5 h

2.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 5 h / 20 °C

3.1: methanol; lithium hydroxide; water / tetrahydrofuran / 3 h / 20 °C

3.2: pH 2

4.1: tetrahydrofuran; water / 0.5 h / 20 °C

With methanol; lithium hydroxide; water; caesium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; water; butanone;