2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Base Information

Chemical Name:2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester
CAS No.:554408-78-5
Molecular Formula:C₂₀H₃₀O₄
Molecular Weight:334.456
Hs Code.:

Synonyms:2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Suppliers and Price of 2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

There total 3 articles about 2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 3282-30-2
pivaloyl chloride

: 554408-71-8
3-hydroxymethyl-2-(4-methoxy-3-methylphenyl)-2-methylcyclopentanol

: 554408-78-5
2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/S0040-4020(03)00236-9

Reference yield:

: 554408-77-4
2-(4-methoxy-3-methyl-phenyl)-2-methyl-3-methylene-cyclopentanol

: 554408-78-5
2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: BH₃*Me₂S / tetrahydrofuran / 20 °C

1.2: 71 percent / aq. NaOH; H₂O₂ / tetrahydrofuran / 0.5 h / 20 °C

2.1: 84 percent / Et₃N; DMAP / CH₂Cl₂ / 0 °C

With dmap; dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4020(03)00236-9

Reference yield:

: 554408-70-7
2-(4-methoxy-3-methylphenyl)-2-methyl-3-methylenecyclopentenone

: 554408-78-5
2,2-dimethyl-propionic acid 3-hydroxy-2-(4-methoxy-3-methyl-phenyl)-2-methyl-cyclopentylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 98 percent / NaBH₄ / ethanol / 0.67 h / 20 °C

2.1: BH₃*Me₂S / tetrahydrofuran / 20 °C

2.2: 71 percent / aq. NaOH; H₂O₂ / tetrahydrofuran / 0.5 h / 20 °C

3.1: 84 percent / Et₃N; DMAP / CH₂Cl₂ / 0 °C

With dmap; sodium tetrahydroborate; dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/S0040-4020(03)00236-9