(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Base Information

Chemical Name:(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate
CAS No.:149606-47-3
Molecular Formula:C₂₁H₃₃NO₅
Molecular Weight:379.497
Hs Code.:

Synonyms:(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Suppliers and Price of (3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

There total 4 articles about (3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1611479-63-0
(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-hydroxy-5-methylhexanoate

: 420-37-1
trimethoxonium tetrafluoroborate

: 149606-47-3
(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Guidance literature:: With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In 1,2-dichloro-ethane; at 0 - 20 ℃; for 18h; Inert atmosphere; Molecular sieve;
DOI:10.3762/bjoc.10.29

Reference yield:

: 202806-77-7
t-butyl-(3R,4S)-4-(N-benzyloxycarbonylamino)-3-hydroxy-5-methyl-hexanoate

: ethyl acetate n-hexane

: 333-27-7
methyl trifluoromethanesulfonate

: 149606-47-3
(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Guidance literature:: With citric acid; lithium hexamethyldisilazane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;

Reference yield:

: 149632-88-2
(3R,4S)-4-(Benzyloxycarbonyl-methyl-amino)-3-methoxy-5-methyl-hexanoic acid methyl ester

: 149606-47-3
(3R,4S)-tert-butyl 4-((benzyloxycarbonyl)(methyl)amino)-3-methoxy-5-methylhexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1N aq. NaOH / dioxane / 3 h / Ambient temperature

2: H₂SO₄ / CH₂Cl₂

With sodium hydroxide; sulfuric acid; In 1,4-dioxane; dichloromethane;
DOI:10.1248/cpb.43.1706