(3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

Base Information

Chemical Name:(3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol
CAS No.:1015445-19-8
Molecular Formula:C₂₀H₂₃NO₃S
Molecular Weight:357.474
Hs Code.:

Synonyms:(3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

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Technology Process of (3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

There total 2 articles about (3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 5720-05-8
4-methylphenylboronic acid

: 420132-18-9
N-(buta-2,3-dien-1-yl)-4-methyl-N-(2-oxoethyl)benzenesulfonamide

: 1015445-19-8
(3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

Guidance literature:: With (S)-SEGPHOS; palladium diacetate; In acetonitrile; at 20 ℃; for 7h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol702966j

Reference yield:

: 5720-07-0
4-methoxyphenylboronic acid

: 99646-28-3,100165-88-6
1,1′-binaphthalene-2,2′-diylbis[bis(4-methylphenyl)phosphine]

: 420132-18-9
N-(buta-2,3-dien-1-yl)-4-methyl-N-(2-oxoethyl)benzenesulfonamide

: 1015445-19-8
(3S,4S)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

: (3R,4R)-4-[1-(4-methylphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

: 1015445-18-7
(3S,4S)-4-[1-(4-methoxyphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

: 1015445-46-1
(3R,4R)-4-[1-(4-methoxyphenyl)ethenyl]-1-[(4-methylphenyl)sulfonyl]-3-pyrrolidinol

Guidance literature:: With palladium diacetate; In acetonitrile; at 20 ℃; for 12h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol702966j