2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine

Base Information

Chemical Name:2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine
CAS No.:190654-77-4
Molecular Formula:C₁₃H₁₁Cl₂N₅
Molecular Weight:308.17
Hs Code.:
DSSTox Substance ID:DTXSID801220837

Synonyms:SCHEMBL3352454;2-chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine;WDQNKEAFSDIEMK-UHFFFAOYSA-N;DTXSID801220837;190654-77-4;2-chloro-6-(3-chloro-phenyl-amino)-9-ethyl-9H-purine

Suppliers and Price of 2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:307.0391508
Heavy Atom Count:20
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN1C=NC2=C(N=C(N=C21)Cl)NC3=CC(=CC=C3)Cl

Technology Process of 2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine

There total 5 articles about 2-Chloro-n-(3-chlorophenyl)-9-ethyl-9h-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 108-42-9
3-chloro-aniline

: 190655-14-2
2,6-dichloro-9-ethyl-9H-purine

: 190654-77-4
2-chloro-N-(3-chlorophenyl)-9-ethyl- 9H-purin-6-amine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 110 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm901069a

Reference yield: 85.0%

: 75-03-6
ethyl iodide

: 190654-76-3
2-chloro-6-(3-chlorophenylamino)-purine

: 190654-77-4
2-chloro-N-(3-chlorophenyl)-9-ethyl- 9H-purin-6-amine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 2h; Ambient temperature;
DOI:10.1016/S0960-894X(98)00691-X

Reference yield:

: 5451-40-1
2,6 dichloropurine

: 190654-77-4
2-chloro-N-(3-chlorophenyl)-9-ethyl- 9H-purin-6-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / pentan-1-ol / 3 h / 100 °C

2: 85 percent / K₂CO₃ / dimethylformamide / 2 h / Ambient temperature

With potassium carbonate; In pentan-1-ol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(98)00691-X