(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Base Information

Chemical Name:(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate
CAS No.:233689-91-3
Molecular Formula:C₁₉H₃₀N₂O₇S
Molecular Weight:430.522
Hs Code.:

Synonyms:(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Suppliers and Price of (S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

There total 3 articles about (S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 124-63-0
methanesulfonyl chloride

: 105562-75-2
N²-(tert-butyloxycarbonyl)-N⁵-(benzyloxycarbonyl)-2(S),5-diaminopentanol

: 233689-91-3
(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1.5h;
DOI:10.1002/1099-0690(200004)2000:7<1219::AID-EJOC1219>3.0.CO;2-P

Reference yield: 77.0%

: 2480-93-5
Boc-Orn(Z)-OH

: 124-63-0
methanesulfonyl chloride

: 233689-91-3
(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Guidance literature:: Boc-Orn(Z)-OH; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -15 ℃; for 0.166667h;

With sodium tetrahydroborate; In tetrahydrofuran; water; for 0.166667h; Cooling with ice;

methanesulfonyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 0.5h; Cooling with ice;

Reference yield:

: 2480-93-5
Boc-Orn(Z)-OH

: 233689-91-3
(S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethyl chloroformate / tetrahydrofuran / 0.25 h / -10 - 0 °C

1.2: 83 percent / NaBH₄ / tetrahydrofuran; methanol / 0 °C

2.1: 80 percent / triethylamine / CH₂Cl₂ / 1.5 h / 0 - 20 °C

With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; dichloromethane; 1.1: Substitution / 1.2: Reduction / 2.1: Substitution;
DOI:10.1002/1099-0690(200004)2000:7<1219::AID-EJOC1219>3.0.CO;2-P