N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide

Base Information

Chemical Name:N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide
CAS No.:70298-82-7
Molecular Formula:C₁₃H₁₉NO
Molecular Weight:205.3
Hs Code.:
European Community (EC) Number:632-748-4
Nikkaji Number:J3.155.779H

Synonyms:N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide;JHICC03007;AKOS003865014;EU-0002427;N-(2,5-Dimethylphenyl)-2,2-dimethylpropionamide;SR-01000408156;SR-01000408156-1;Z27670366

Suppliers and Price of N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C)NC(=O)C(C)(C)C

Technology Process of N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide

There total 4 articles about N-(2,5-dimethylphenyl)-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 32597-29-8
N-(3-methylphenyl)-2,2-dimethylpropanamide

: 112359-25-8
5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate

: 70298-82-7
2’,5’-dimethylpivalanilide

Guidance literature:: With palladium diacetate; copper(II) acetate monohydrate; trifluoroacetic acid; In 1,2-dichloro-ethane; at 50 ℃; for 6h; Sealed tube;
DOI:10.1021/acs.orglett.7b03813

Reference yield:

: 95-78-3
2,5-Dimethylaniline

: 3282-30-2
pivaloyl chloride

: 70298-82-7
2’,5’-dimethylpivalanilide

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1021/jm00401a024

Reference yield:

: 3282-30-2
pivaloyl chloride

: 108-44-1
1-amino-3-methylbenzene

: 70298-82-7
2’,5’-dimethylpivalanilide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / 0 - 25 °C

2: copper(II) acetate monohydrate; palladium diacetate; trifluoroacetic acid / 1,2-dichloro-ethane / 6 h / 50 °C / Sealed tube

With palladium diacetate; copper(II) acetate monohydrate; triethylamine; trifluoroacetic acid; In 1,2-dichloro-ethane;
DOI:10.1021/acs.orglett.7b03813