4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane
• CAS No.: 1073339-20-4
• Molecular Formula: C₁₂H₁₃BF₄O₂
• Molecular Weight: 276.039
• Mol file: 1073339-20-4.mol

Synonyms:4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

99%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane

There total 4 articles about 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Pentafluorobenzene (363-72-4) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane (1073339-20-4)

Guidance literature:

With bis(1,3-dimesityl-1H-imidazol-2(3H)-ylidene)nickel⁽⁰⁾; C₃₂H₄₁O₆P₂Rh; cesium fluoride; In 1,3,5-trimethyl-benzene; at 25 ℃; for 6h; regioselective reaction; Irradiation; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.8b09790

Reference yield: 81.0%

Pentafluorobenzene (363-72-4) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane (1073339-11-3) + 2,3,4,6-tetrafluorophenylboronic acid pinacol ester (1111096-18-4) + 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane (1073339-20-4) + 4,4,5,5-tetramethyl-2-(2,3,4,5,6-pentafluorophenyl)-1,3,2-dioxaborolane (325142-81-2)

Guidance literature:

With ((CH₃)5C₅)Ir(P(CH₃)3)H₂; ((CH₃)5C₅)Ir(P(CH₃)3)H((CH₃)4C₂O₂B); In further solvent(s); byproducts: H2; catalyst generated in sity; ((CH3)5C5)IrH2(PMe3) and HB((CH3)4C2O2) dissolved in C6F5H; heated at 150°C for 18 h;

DOI:10.1021/ja0013069

Reference yield:

1,2,3,4-tetrafluorobenzene (551-62-2) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(2,3,4,5-tetrafluorophenyl)-1,3,2-dioxaborolane (1073339-20-4)

Guidance literature:

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; at 80 ℃; for 18h; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201208203

upstream raw materials:

Pentafluorobenzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

1,2,3,4-tetrafluorobenzene

bis(pinacol)diborane

Downstream raw materials:

C₁₄H₁₀F₄

Phenyl(2,3,4,5-tetrafluorphenyl)ethin