Technology Process of methyl 2-(4-(4-oxobutyl)phenyl)acetate
There total 3 articles about methyl 2-(4-(4-oxobutyl)phenyl)acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide;
In
water; ethyl acetate;
at 0 ℃;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate
2: potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate / water; ethyl acetate / 0 °C
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; potassium bromide;
In
methanol; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethylamine; tetrakis(triphenylphosphine) palladium(0); copper(l) iodide / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere; Reflux
2: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate
3: potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate / water; ethyl acetate / 0 °C
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; diethylamine; potassium bromide;
In
tetrahydrofuran; methanol; water; ethyl acetate;
