N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Base Information

Chemical Name:N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide
CAS No.:1201662-22-7
Molecular Formula:C₂₇H₂₂Cl₂FNO₃S
Molecular Weight:530.447
Hs Code.:

Synonyms:N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Suppliers and Price of N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

There total 7 articles about N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1201662-21-6
3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxy-N-(4-(hydroxy(phenyl)methyl)benzyl)benzenesulfonamide

: 1201662-22-7
N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Guidance literature:: With sodium tetrahydroborate; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield:

: 918402-06-9
methyl 4-((4-fluorobenzylamino)methyl)benzoate

: 1201662-22-7
N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: triethylamine / tetrahydrofuran / 2 h / 20 °C

2.1: water; sodium hydroxide / tetrahydrofuran; methanol / 3 h / 20 °C

2.2: 0 °C / pH 3 - 4

3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C

3.2: 1 h / 20 °C

4.1: tetrahydrofuran; diethyl ether / 20 °C

5.1: sodium tetrahydroborate / tetrahydrofuran / 1 h / 0 °C

6.1: sodium tetrahydroborate; trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

With sodium tetrahydroborate; oxalyl dichloride; water; triethylamine; N,N-dimethyl-formamide; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane;

Reference yield:

: 1201663-69-5
4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-benzoic acid

: 1201662-22-7
N-(4-benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C

1.2: 1 h / 20 °C

2.1: tetrahydrofuran; diethyl ether / 20 °C

3.1: sodium tetrahydroborate / tetrahydrofuran / 1 h / 0 °C

4.1: sodium tetrahydroborate; trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

With sodium tetrahydroborate; oxalyl dichloride; N,N-dimethyl-formamide; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;