4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Base Information

Chemical Name:4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide
CAS No.:1201663-72-0
Molecular Formula:C₂₃H₂₁Cl₂FN₂O₅S
Molecular Weight:527.401
Hs Code.:

Synonyms:4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Suppliers and Price of 4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

There total 5 articles about 4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1201663-69-5
4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-benzoic acid

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 1201663-72-0
4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Guidance literature:: 4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃;

N,O-dimethylhydroxylamine*hydrochloride; With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 918402-06-9
methyl 4-((4-fluorobenzylamino)methyl)benzoate

: 1201663-72-0
4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / tetrahydrofuran / 2 h / 20 °C

2.1: water; sodium hydroxide / tetrahydrofuran; methanol / 3 h / 20 °C

2.2: 0 °C / pH 3 - 4

3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C

3.2: 1 h / 20 °C

With oxalyl dichloride; water; triethylamine; N,N-dimethyl-formamide; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: C₂₂H₁₈Cl₂FNO₅S

: 1201663-72-0
4-((3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxyphenylsulfonamido)methyl)-N-methoxy-N-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; sodium hydroxide / tetrahydrofuran; methanol / 3 h / 20 °C

1.2: 0 °C / pH 3 - 4

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C

2.2: 1 h / 20 °C

With oxalyl dichloride; water; N,N-dimethyl-formamide; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;