(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

Base Information

Chemical Name:(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride
CAS No.:458560-11-7
Molecular Formula:C₁₉H₂₄N₂O₅S₂*ClH
Molecular Weight:461.003
Hs Code.:

Synonyms:(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

Suppliers and Price of (R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

Chemical Property:

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Technology Process of (R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

There total 2 articles about (R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 458558-89-9
4-{(R)-carboxy-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-methyl}piperidine-1-carboxylic acid tert-butyl ester

: 458560-11-7
(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

Guidance literature:: With hydrogenchloride; at 20 ℃;
DOI:10.1021/jm801394m

Reference yield:

: 458560-11-7
(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

Guidance literature:

Reference yield: 89.6%

: 458560-11-7
(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-piperidin-4-yl-acetic acid hydrochloride

: 78-84-2
isobutyraldehyde

: 458560-12-8
(R)-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-[1-iso-butylpiperidin-4-yl]-acetic acid

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In 1,1-dichloroethane; at 20 ℃; Inert atmosphere;
DOI:10.1021/jm801394m