2-methoxy-N--4-methoxyphenyl-benzenamine

Base Information

• Chemical Name: 2-methoxy-N--4-methoxyphenyl-benzenamine
• CAS No.: 58751-07-8
• Molecular Formula: C₁₄H₁₅NO₂
• Molecular Weight: 229.279
• Mol file: 58751-07-8.mol

Synonyms:4-methoxy-N-(2-methoxyphenyl)benzenamine

Chemical Property of 2-methoxy-N--4-methoxyphenyl-benzenamine

Chemical Property:

• Melting Point: 69.0 to 73.0 °C
• Boiling Point: 354.3±27.0 °C(Predicted)
• PKA: 1.42±0.40(Predicted)
• Density: 1.126±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxy-N-(4-methoxyphenyl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-N--4-methoxyphenyl-benzenamine

There total 16 articles about 2-methoxy-N--4-methoxyphenyl-benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-Chloroanisole (766-51-8) + 4-methoxy-aniline (104-94-9) → 4-methoxy-N-(2-methoxyphenyl)benzenamine (58751-07-8)

Guidance literature:

With C₆₃H₅₄Cl₃N₃OPd; potassium 2-methylbutan-2-olate; In 1,4-dioxane; at 100 ℃; for 2h;

DOI:10.1021/acs.joc.6b02867

Reference yield: 85.0%

2-[(4-methoxyphenyl)amino]cyclohex-2-en-1-one (105553-63-7) + methyl iodide (74-88-4) → 4-methoxy-N-(2-methoxyphenyl)benzenamine (58751-07-8)

Guidance literature:

2-[(4-methoxyphenyl)amino]cyclohex-2-en-1-one; With palladium diacetate; In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

methyl iodide; With potassium carbonate; In acetone; for 2h; Reflux; Inert atmosphere;

DOI:10.1055/s-0032-1317175 DOI:10.1055/s-0032-1317175

Reference yield: 85.0%

o-Methoxyphenyllead(IV) triacetate (68490-98-2) + 4-methoxy-aniline (104-94-9) → 4-methoxy-N-(2-methoxyphenyl)benzenamine (58751-07-8)

Guidance literature:

copper diacetate; In dichloromethane; for 0.5h; Ambient temperature;

upstream raw materials:

o-Methoxyphenyllead(IV) triacetate

4-methoxy-aniline

methyl iodide

1-bromo-4-methoxy-benzene

Downstream raw materials:

N²,N²,N^2',N^2',N⁷,N⁷,N^7',N^7'-octakis(2-methoxypheny)-9,9'-spirobi[fluorene]-2,2',7,7'-tetraamine

Refernces

• 1、 Guan, Xinyu,Zhu, Haoran,Driver, Tom G.. "Cu-Catalyzed Cross-Coupling of Nitroarenes with Aryl Boronic Acids to Construct Diarylamines". . p. 12417 - 12422. Retrieved 2021/10/12.
• 2、 -. "Hole transporting material taking carbazoles bonded with tetracarbon chain as core as well as preparation method and application of hole transporting material". Paragraph 0080; 0092; 0093; 0094; 0095. . Retrieved 2019/07/04.