(S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE

Base Information

Chemical Name:(S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE
CAS No.:851394-29-1
Molecular Formula:C14H17 N5 O2
Molecular Weight:287.32
Hs Code.:
Mol file:851394-29-1.mol

Synonyms:1-Pyrrolidinecarboxylicacid, 2-(1H-tetrazol-5-ylmethyl)-, phenylmethyl ester, (2S)- (9CI)

Suppliers and Price of (S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE 95.00%
5MG
$ 501.74

Total 3 raw suppliers

Chemical Property of (S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE

Chemical Property:

Vapor Pressure:5.05E-10mmHg at 25°C
Refractive Index:1.62
Boiling Point:497.2°C at 760 mmHg
Flash Point:254.5°C
PSA：84.00000
Density:1.34g/cm³
LogP:1.48130

Purity/Quality:

99.3% ^*data from raw suppliers

(S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE

There total 5 articles about (S)-1-CBZ-2-(1H-TETRAZOL-5-YLMETHYL)PYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 72500-25-5
(S)-benzyl 2-(cyanomethyl)pyrrolidine-1-carboxylate

: 851394-29-1
2-(1H-tetrazol-5-ylmethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: With sodium azide; ammonium chloride; at 150 ℃;
DOI:10.1055/s-2005-862392

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 851394-29-1
2-(1H-tetrazol-5-ylmethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂

2: pyridine / 20 °C

3: 93 percent / 50 °C

4: 73 percent / NaN₃; NH₄Cl / 150 °C

With pyridine; sodium azide; ammonium chloride; triethylamine; In dichloromethane;
DOI:10.1055/s-2005-862392

Reference yield:

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 851394-29-1
2-(1H-tetrazol-5-ylmethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂

2: pyridine / 20 °C

3: 93 percent / 50 °C

4: 73 percent / NaN₃; NH₄Cl / 150 °C

With pyridine; sodium azide; ammonium chloride; triethylamine; In dichloromethane;
DOI:10.1055/s-2005-862392