2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Base Information

• Chemical Name: 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
• CAS No.: 83126-69-6
• Molecular Formula: C₁₉H₂₆O₂
• Molecular Weight: 286.414
• Mol file: 83126-69-6.mol

Synonyms:2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Chemical Property of 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

There total 3 articles about 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

carbon monoxide (201230-82-2) + (-)-menthol (2216-51-5) + phenylacetylene (536-74-3) → (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl cinnamate (16205-99-5) + 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester (83126-69-6)

Guidance literature:

With toluene-4-sulfonic acid; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 100 ℃; for 2h; under 7600 Torr;

DOI:10.1080/00397919708007083

Reference yield:

(-)-menthol (2216-51-5) + 2-phenylacrylyl chloride (51491-68-0) → 2-Phenyl-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester (83126-69-6)

Guidance literature:

With pyridine; In benzene; Yield given; Ambient temperature;

Reference yield:

(-)-menthol (2216-51-5) → 2-phenyl-acrylic acid menthyl ester (83126-69-6)

Guidance literature:

With pyridine; benzene;

upstream raw materials:

(-)-menthol

2-phenylacrylyl chloride

carbon monoxide

phenylacetylene