2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester

Base Information

Chemical Name:2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester
CAS No.:143230-42-6
Molecular Formula:C₁₆H₁₇ClN₂O₅
Molecular Weight:352.774
Hs Code.:
Mol file:143230-42-6.mol

Synonyms:2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3,3-dimethoxypropionic acid methyl ester

Suppliers and Price of 2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneaceticAcidMethylEster
10mg
$ 330.00

Medical Isotopes, Inc.
2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneaceticAcidMethylEster
25 mg
$ 1075.00

Medical Isotopes, Inc.
2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneaceticAcidMethylEster
10 mg
$ 800.00

Total 2 raw suppliers

Chemical Property of 2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester

Chemical Property:

Solubility.:Acetone, DCM, Ethyl Acetate, Methanol

Purity/Quality:

99.9% ^*data from raw suppliers

2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneaceticAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneacetic Acid Methyl Ester is an impurity of Azoxystrobin (A965150), an strobilurin fungicide.

Technology Process of 2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester

There total 12 articles about 2-[(6-Chloro-4-pyriMidinyl)oxy]-α-(diMethoxyMethyl)benzeneacetic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1193-21-1
4,6-dichloropyrimidine

: 40800-90-6
3-(α-methoxy)methylene benzofuran-2-(3H)-ketone

: 124-41-4
sodium methylate

: 143230-42-6
2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3,3-dimethoxypropionic acid methyl ester

Guidance literature:: 3-(α-methoxy)methylene benzofuran-2-(3H)-ketone; sodium methylate; With 2-methyl-1,4-divinylpiperazine; In methanol; acetonitrile; at 15 - 20 ℃; for 0.5h;

4,6-dichloropyrimidine; In methanol; acetonitrile; for 1h; Solvent; Temperature;

Reference yield: 76.0%

: 1193-21-1
4,6-dichloropyrimidine

: 175971-61-6
2-(2-hydroxyphenyl)-3,3-dimethoxypropionic acid methyl ester

: 143230-42-6
2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3,3-dimethoxypropionic acid methyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 8h;
DOI:10.1002/jccs.201200295

Reference yield:

: 1193-21-1
4,6-dichloropyrimidine

: 40800-90-6
3-(α-methoxy)methylene benzofuran-2-(3H)-ketone

: 143230-42-6
2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3,3-dimethoxypropionic acid methyl ester

: 131860-97-4
(E)-methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxy-propenoate

Guidance literature:: With sodium methylate; potassium carbonate; 2-methyl-1,4-diazabicyclo [2,2,2]octane; In methanol; Methyl formate; toluene; at 5 - 20 ℃; for 1.5h; Reagent/catalyst; Temperature; Overall yield = 92.3 %Chromat.; Inert atmosphere;