2,5-Dichloro-4-hydroxypyridine

Base Information

Chemical Name:2,5-Dichloro-4-hydroxypyridine
CAS No.:847664-65-7
Molecular Formula:C₅H₃Cl₂NO
Molecular Weight:163.991
Hs Code.:2933399990
European Community (EC) Number:640-918-4
DSSTox Substance ID:DTXSID80955928
Nikkaji Number:J1.537.731C,J2.142.732B
Wikidata:Q82935730
Mol file:847664-65-7.mol

Synonyms:2,5-Dichloro-4-hydroxypyridine;2,5-Dichloropyridin-4-ol;847664-65-7;343781-57-7;2,5-dichloro-1H-pyridin-4-one;4-Pyridinol, 2,5-dichloro-;2,5-Dichloropyridin-4(1H)-one;MFCD01861982;2,5-Dichloropyridine-4-ol;SCHEMBL1425056;AMY7979;DTXSID80955928;RJKYZTVQNJPAGX-UHFFFAOYSA-N;2,5-Dichloropyridine-4(1H)-one;XIB66465;AKOS015850271;AKOS015851103;PS-5418;AC-33434;SY036594;CS-0149625;FT-0600179;FT-0691452;EN300-370637;A914963;J-507322;propanamide,n-[(8-hydroxy-7-quinolinyl)phenylmethyl]-2-methyl

Suppliers and Price of 2,5-Dichloro-4-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Dichloro-4-hydroxypyridine
25g
$ 75.00

SynQuest Laboratories
2,5-Dichloro-4-hydroxypyridine
1 g
$ 309.00

SynQuest Laboratories
2,5-Dichloro-4-hydroxypyridine
500 mg
$ 172.00

SynQuest Laboratories
2,5-Dichloro-4-hydroxypyridine
250 mg
$ 124.00

Frontier Specialty Chemicals
2,5-Dichloro-4-hydroxypyridine 98%
1g
$ 120.00

Frontier Specialty Chemicals
2,5-Dichloro-4-hydroxypyridine 98%
5g
$ 480.00

Crysdot
2,5-Dichloropyridin-4-ol 97%
5g
$ 832.00

Crysdot
2,5-Dichloropyridin-4-ol 97%
250mg
$ 111.00

Crysdot
2,5-Dichloropyridin-4-ol 97%
1g
$ 277.00

Crysdot
2,5-Dichloropyridin-4-ol 97%
10g
$ 1340.00

Total 14 raw suppliers

Chemical Property of 2,5-Dichloro-4-hydroxypyridine

Chemical Property:

Density:1.561±0.06 g/cm3 (20 ºC 760 Torr)
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:162.9591691
Heavy Atom Count:9
Complexity:207

Purity/Quality:

98% ^*data from raw suppliers

2,5-Dichloro-4-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(NC=C(C1=O)Cl)Cl

Technology Process of 2,5-Dichloro-4-hydroxypyridine

There total 2 articles about 2,5-Dichloro-4-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 847664-64-6
(2,5-dichloropyridin-4-yl)boronic acid

: 343781-57-7,847664-65-7
2,5-dichloro-4-hydroxypyridine

Guidance literature:: With dihydrogen peroxide; In dichloromethane; water; at 20 ℃; for 20h;
DOI:10.1016/j.tet.2004.12.006

Reference yield:

: 16110-09-1
2,5 dichloropyridine

: 343781-57-7,847664-65-7
2,5-dichloro-4-hydroxypyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: diisopropylamine; n-BuLi / tetrahydrofuran; hexane / 1 h / -80 °C

1.2: 56 percent / triisopropyl borate / tetrahydrofuran; hexane / -80 - 20 °C

2.1: 22 percent / hydrogen peroxide / CH₂Cl₂; H₂O / 20 h / 20 °C

With n-butyllithium; dihydrogen peroxide; diisopropylamine; In tetrahydrofuran; hexane; dichloromethane; water;
DOI:10.1016/j.tet.2004.12.006