Technology Process of C19H28OSi
There total 6 articles about C19H28OSi which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C12H22OSi;
With
n-butyllithium; sodium iodide;
In
tetrahydrofuran;
at -78 ℃;
for 2h;
Inert atmosphere;
benzyl bromide;
In
tetrahydrofuran;
at 50 ℃;
for 10h;
Inert atmosphere;
DOI:10.1002/anie.201405215
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-butyllithium / tetrahydrofuran / -78 °C
2.1: n-butyllithium / diethyl ether / 0 - 20 °C
3.1: potassium carbonate; methanol / 2 h / 20 °C
4.1: sodium tetrahydroborate / methanol
5.1: 1H-imidazole / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
6.1: n-butyllithium; sodium iodide / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
6.2: 10 h / 50 °C / Inert atmosphere
With
1H-imidazole; methanol; sodium tetrahydroborate; n-butyllithium; potassium carbonate; sodium iodide;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane;
DOI:10.1002/anie.201405215
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / diethyl ether / 0 - 20 °C
2.1: potassium carbonate; methanol / 2 h / 20 °C
3.1: sodium tetrahydroborate / methanol
4.1: 1H-imidazole / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
5.1: n-butyllithium; sodium iodide / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
5.2: 10 h / 50 °C / Inert atmosphere
With
1H-imidazole; methanol; sodium tetrahydroborate; n-butyllithium; potassium carbonate; sodium iodide;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane;
DOI:10.1002/anie.201405215
