3'-Chloro-5'-fluoroacetophenone

Base Information

Chemical Name:3'-Chloro-5'-fluoroacetophenone
CAS No.:842140-52-7
Molecular Formula:C8H6ClFO
Molecular Weight:172.586
Hs Code.:2914700090
European Community (EC) Number:642-847-4
DSSTox Substance ID:DTXSID50373933
Wikidata:Q82162343
Mol file:842140-52-7.mol

Synonyms:3'-Chloro-5'-fluoroacetophenone;842140-52-7;1-(3-chloro-5-fluorophenyl)ethanone;3-chloro-5-fluoroacetophenone;1-(3-CHLORO-5-FLUOROPHENYL)ETHAN-1-ONE;1-(3-chloro-5-fluoro-phenyl)-ethanone;MFCD04115834;3-chloro-5-fluoro acetophenone;SCHEMBL1160981;3'-Fluoro-5'-chloroacetophenone;DTXSID50373933;BVKHCVHYQNGCSC-UHFFFAOYSA-N;AMY14600;CK2560;AKOS006345921;AB20622;AS-18564;C3288;CS-0128881;FT-0692119;A19699;EN300-314771;Z1201622911

Suppliers and Price of 3'-Chloro-5'-fluoroacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3''-Chloro-5''-fluoroacetophenone
50mg
$ 45.00

TCI Chemical
3'-Chloro-5'-fluoroacetophenone
5G
$ 163.00

TCI Chemical
3'-Chloro-5'-fluoroacetophenone
1G
$ 48.00

Matrix Scientific
3'-Chloro-5'-fluoroacetophenone
5g
$ 112.00

Matrix Scientific
3'-Chloro-5'-fluoroacetophenone
25g
$ 441.00

Crysdot
1-(3-Chloro-5-fluorophenyl)ethanone 97%
25g
$ 419.00

Chemenu
1-(3-Chloro-5-fluorophenyl)ethanone 95+%
25g
$ 392.00

Apolloscientific
3'-Chloro-5'-fluoroacetophenone 97%
5g
$ 135.00

Apolloscientific
3'-Chloro-5'-fluoroacetophenone 97%
10g
$ 237.00

American Custom Chemicals Corporation
3'-CHLORO-5'-FLUOROACETOPHENONE 95.00%
5G
$ 879.25

Total 38 raw suppliers

Chemical Property of 3'-Chloro-5'-fluoroacetophenone

Chemical Property:

Melting Point:51-54 °C
Boiling Point:237.1 °C at 760 mmHg
Flash Point:97.2 °C
PSA：17.07000
Density:1.258 g/cm³
LogP:2.68170
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Soluble in diethyl ether
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:172.0091207
Heavy Atom Count:11
Complexity:160

Purity/Quality:

97% ^*data from raw suppliers

3''-Chloro-5''-fluoroacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=CC(=C1)Cl)F
Uses 3'-Chloro-5'-fluoroacetophenone is used as a medicament for the treatment and prophylaxis of diseases in humans and animals.

Technology Process of 3'-Chloro-5'-fluoroacetophenone

There total 2 articles about 3'-Chloro-5'-fluoroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.1%

: 1262882-69-8
3-chloro-5-fluoro-N-methoxy-N-methylbenzamide

: 75-16-1
methylmagnesium bromide

: 842140-52-7
1-(3-chloro-5-fluorophenyl)ethan-1-one

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃; for 2h;

Reference yield:

: 886496-62-4
3-chloro-5-fluorobenzoyl chloride

: 842140-52-7
1-(3-chloro-5-fluorophenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 12 h / 20 °C

2: tetrahydrofuran / 2 h / 0 - 20 °C

With pyridine; In tetrahydrofuran; dichloromethane;