(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid

Base Information

Chemical Name:(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid
CAS No.:1394131-74-8
Molecular Formula:C₁₁H₁₀N₂O₄
Molecular Weight:234.211
Hs Code.:
DSSTox Substance ID:DTXSID701168238
Wikidata:Q27451365
ChEMBL ID:CHEMBL2179989

Synonyms:CHEMBL2179989;(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid;DTXSID701168238;BDBM50397960;Q27451365;2-Butenoic acid, 4-[[3-(aminocarbonyl)phenyl]amino]-4-oxo-, (2Z)-;1394131-74-8

Suppliers and Price of (2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:234.06405680
Heavy Atom Count:17
Complexity:351

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)NC(=O)C=CC(=O)O)C(=O)N
Isomeric SMILES:C1=CC(=CC(=C1)NC(=O)/C=C\C(=O)O)C(=O)N

Technology Process of (2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid

There total 1 articles about (2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 108-31-6
maleic anhydride

: 3544-24-9
3-Aminobenzamide

: 1394131-74-8
(Z)-4-(3-carbamoylphenylamino)-4-oxobut-2-enoic acid

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 18h;
DOI:10.1021/jm300746d

Reference yield: 72.0%

: 1394131-74-8
(Z)-4-(3-carbamoylphenylamino)-4-oxobut-2-enoic acid

: 180698-19-5
1-(1,1′-biphenyl-4-yl)piperazine

: MCD-106

Guidance literature:: (Z)-4-(3-carbamoylphenylamino)-4-oxobut-2-enoic acid; 1-(1,1′-biphenyl-4-yl)piperazine; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; Inert atmosphere;

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; for 1h; Inert atmosphere;
DOI:10.1016/j.bmcl.2017.04.089