1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Base Information

Chemical Name:1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline
CAS No.:1586765-20-9
Molecular Formula:C₂₁H₁₈FN₅O
Molecular Weight:375.405
Hs Code.:

Synonyms:1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Suppliers and Price of 1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

There total 3 articles about 1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1586765-14-1
5-methyl-1-(4-methoxyphenyl)-N-[2-(5-fluoro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

: 1586765-20-9
1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Guidance literature:: With phosphorus pentoxide; trichlorophosphate; In toluene; at 110 ℃; for 12h;
DOI:10.1134/S1070428014020225

Reference yield:

: 88958-25-2
5-methyl-1-(4-methoxyphenyl)-1,2,3-triazol-4-carbonyl chloride

: 1586765-20-9
1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / 1,2-dichloro-ethane; dichloromethane / 12 h / 25 °C

2: trichlorophosphate; phosphorus pentoxide / toluene / 12 h / 110 °C

With phosphorus pentoxide; potassium carbonate; trichlorophosphate; In dichloromethane; 1,2-dichloro-ethane; toluene; 2: |Bischler-Napieralski Reaction;
DOI:10.1134/S1070428014020225

Reference yield:

: 31802-54-7
1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

: 1586765-20-9
1-[5-methyl-1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl]-6-fluoro-4,9-dihydro-3H-β-carboline

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride

2: potassium carbonate / 1,2-dichloro-ethane; dichloromethane / 12 h / 25 °C

3: trichlorophosphate; phosphorus pentoxide / toluene / 12 h / 110 °C

With thionyl chloride; phosphorus pentoxide; potassium carbonate; trichlorophosphate; In dichloromethane; 1,2-dichloro-ethane; toluene; 3: |Bischler-Napieralski Reaction;
DOI:10.1134/S1070428014020225