(S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Base Information

Chemical Name:(S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine
CAS No.:825612-43-9
Molecular Formula:C29H38 N2 O S
Molecular Weight:462.7
Hs Code.:
Mol file:825612-43-9.mol

Synonyms:(S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine;(S)-S-Methyl-S-phenyl-N-{2-[(2,4,6-triisopropylphenyl)methylamino]phenyl}sulfoximine

Suppliers and Price of (S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-S-Methyl-S-phenyl-N-{2-[(2,4,6-triisopropylphenyl)methylamino]phenyl}sulfoximine ≥97.0% (HPLC)
500mg
$ 465.00

Sigma-Aldrich
(S)-S-Methyl-S-phenyl-N-{2-[(2,4,6-triisopropylphenyl)methylamino]phenyl}sulfoximine ≥97.0% (HPLC)
100mg
$ 83.40

American Custom Chemicals Corporation
(S)-S-METHYL-S-PHENYL-N-[2-[(2,4,6-TRIISOPROPYLPHENYL)METHYLAMINO]PHENYL]SULFOXIMINE 95.00%
500MG
$ 1075.71

American Custom Chemicals Corporation
(S)-S-METHYL-S-PHENYL-N-[2-[(2,4,6-TRIISOPROPYLPHENYL)METHYLAMINO]PHENYL]SULFOXIMINE 95.00%
100MG
$ 724.86

Total 4 raw suppliers

Chemical Property of (S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Chemical Property:

Melting Point:124-127 °C
PSA：49.84000
LogP:9.39600

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-S-Methyl-S-phenyl-N-{2-[(2,4,6-triisopropylphenyl)methylamino]phenyl}sulfoximine ≥97.0% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Ligand used with copper for asymmetric aldol reactions.

Technology Process of (S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

There total 7 articles about (S)-N-[2-(2,4,6-Triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 24249-82-9
2,4,6-triisopropylbenzaldehyde

: 825612-38-2
(S)-N-(2-aminophenyl)-S-methyl-S-phenylsulfoximine

: 825612-43-9,948831-14-9
(S)-N-[2-(2,4,6-triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Guidance literature:: With sodium tetrahydroborate; acetic acid; In methanol; at 20 ℃;
DOI:10.1002/anie.200460953

Reference yield:

: 4381-25-3,33903-50-3,60933-65-5,81162-81-4
(S)-S-methyl-S-phenylsulfoximine

: 825612-43-9,948831-14-9
(S)-N-[2-(2,4,6-triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / rac-BINAP; Cs₂CO₃ / Pd(OAc)2 / toluene / 24 h / 110 °C

2: 83 percent / aq. acetic acid; Fe / ethanol / 3 h / Heating

3: glacial acetic acid / methanol / 3 h / 20 °C

4: 1.14 g / NaBH₄ / methanol / 20 °C

With sodium tetrahydroborate; iron; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; palladium diacetate; In methanol; ethanol; toluene;
DOI:10.1002/chem.200500497

Reference yield:

: 577-19-5
2-nitrophenyl bromide

: 825612-43-9,948831-14-9
(S)-N-[2-(2,4,6-triisopropylbenzylamino)phenyl]-S-methyl-S-phenylsulfoximine

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / rac-BINAP; Cs₂CO₃ / Pd(OAc)2 / toluene / 24 h / 110 °C

2: 83 percent / aq. acetic acid; Fe / ethanol / 3 h / Heating

3: glacial acetic acid / methanol / 3 h / 20 °C

4: 1.14 g / NaBH₄ / methanol / 20 °C

With sodium tetrahydroborate; iron; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; palladium diacetate; In methanol; ethanol; toluene;
DOI:10.1002/chem.200500497