(((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane)

Base Information

• Chemical Name: (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane)
• CAS No.: 1111715-86-6
• Molecular Formula: C₂₀H₃₇IO₂Si₂
• Molecular Weight: 492.588
• Mol file: 1111715-86-6.mol

Synonyms:(((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane)

Chemical Property of (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane)

There total 1 articles about (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

tert-butyldimethylsilyl chloride (18162-48-6) + (3-hydroxymethyl-5-iodo-phenyl)-methanol (859238-49-6) → (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane) (1111715-86-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1039/b901631g

Reference yield: 95.0%

di-tert-butyl dicarbonate (24424-99-5) + (((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane) (1111715-86-6) → tert-butyl 3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)benzoate

Guidance literature:

(((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane); With n-butyllithium; In hexane; toluene; at 10 ℃; for 2h; Inert atmosphere;

di-tert-butyl dicarbonate; In hexane; toluene; at -10 ℃; for 1h;

Reference yield: 91.0%

(((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane) (1111715-86-6) + methyl chloroformate (79-22-1) → methyl 3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)benzoate

Guidance literature:

(((5-iodo-1,3-phenylene)bis(methylene))bis(oxy))bis(tert-butyldimethylsilane); With n-butyllithium; In tetrahydrofuran; hexane; toluene; at -10 ℃; for 2h; Inert atmosphere;

methyl chloroformate; In tetrahydrofuran; hexane; toluene; at -50 ℃; for 2h;

upstream raw materials:

tert-butyldimethylsilyl chloride

(3-hydroxymethyl-5-iodo-phenyl)-methanol

Downstream raw materials:

3',5'-bis(tert-butyldimethylsilyloxymethyl)-2,2,2-trifluoromethylacetophenone

methyl 3,5-bis(bromomethyl)benzoate