N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Base Information

Chemical Name:N-(4'-methoxybenzenesulphonyl)-L-glutamic acid
CAS No.:99289-76-6
Molecular Formula:C₁₂H₁₅NO₇S
Molecular Weight:317.32
Hs Code.:
European Community (EC) Number:619-418-5
Nikkaji Number:J562.891A

Synonyms:N-(4'-methoxybenzenesulphonyl)-L-glutamic acid;99289-76-6;SCHEMBL785348;AKOS008944010;(2S)-2-[(4-methoxyphenyl)sulfonylamino]pentanedioic Acid

Suppliers and Price of N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:317.05692299
Heavy Atom Count:21
Complexity:463

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)S(=O)(=O)NC(CCC(=O)O)C(=O)O

Technology Process of N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

There total 3 articles about N-(4'-methoxybenzenesulphonyl)-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 99289-76-6
N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Guidance literature:: With sodium hydroxide; at 70 ℃;

Reference yield:

: 142-47-2
monosodium L-glutamate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 99289-76-6
N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Guidance literature:: monosodium L-glutamate; With sodium hydroxide; In water; at 35 - 40 ℃;

4-methoxy-phenyl-sulphonyl chloride; With sodium hydroxide; In water; at 50 - 80 ℃; for 1h; pH=8 - 11;

With hydrogenchloride; In water; butanone; at 20 - 25 ℃; pH=1;

Reference yield:

: 100-66-3
methoxybenzene

: 99289-76-6
N-(4'-methoxybenzenesulphonyl)-L-glutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 0 - 5 °C

2: sodium hydroxide

With chlorosulfonic acid; sodium hydroxide;
DOI:10.1007/s00044-017-1858-1