(S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Base Information

Chemical Name:(S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid
CAS No.:1033805-86-5
Molecular Formula:C₃₂H₃₂F₃N₅O₆
Molecular Weight:639.631
Hs Code.:

Synonyms:(S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Suppliers and Price of (S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

There total 2 articles about (S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1033805-85-4
1-[4-(6-methoxypyridin-2-yl)phenyl]-2,2,2-trifluoroethanol

: 1033804-86-2
(S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid

: 1033805-86-5
(S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Guidance literature:: 1-[4-(6-methoxypyridin-2-yl)phenyl]-2,2,2-trifluoroethanol; With caesium carbonate; In 1,3-dioxane; for 0.0833333h;

(S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid; In 1,4-dioxane; at 110 ℃;

Reference yield:

: 618092-16-3
4-(6-methoxypyridin-2-yl)benzaldehyde

: 1033805-86-5
(S)-3-[4-(2-amino-6-{2,2,2-trifluoro-1-[4-(6-methoxypyridin-2-yl)phenyl]ethoxy}pyrimidin-4-yl)phenyl]-2-tert-butoxycarbonylaminopropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C

2.1: caesium carbonate / 1,4-dioxane / 0.08 h

2.2: 110 °C

With tetrabutyl ammonium fluoride; caesium carbonate; In tetrahydrofuran; 1,4-dioxane;