2-(2,3-dichlorophenyl)-5,5-diMethyl-1,3,2-dioxaborinane

Base Information

• Chemical Name: 2-(2,3-dichlorophenyl)-5,5-diMethyl-1,3,2-dioxaborinane
• CAS No.: 1255760-30-5
• Molecular Formula: C₁₂H₁₅BCl₂O₂
• Molecular Weight: 272.967
• Mol file: 1255760-30-5.mol

Synonyms:1,2-dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)benzene

Chemical Property of 2-(2,3-dichlorophenyl)-5,5-diMethyl-1,3,2-dioxaborinane

Chemical Property:

• Boiling Point: 350.0±32.0 °C(Predicted)
• Density: 1.20±0.1 g/cm3(Predicted)

Purity/Quality:

99%,98%, ^*data from raw suppliers

2-(2,3-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,3-dichlorophenyl)-5,5-diMethyl-1,3,2-dioxaborinane

There total 2 articles about 2-(2,3-dichlorophenyl)-5,5-diMethyl-1,3,2-dioxaborinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,2-dichloro-benzene (95-50-1) + bis(pinacol)diborane (73183-34-3) → 1,2-dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)benzene (1255760-30-5) + 2-(3,4-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (401797-02-2)

Guidance literature:

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In tetrahydrofuran; at 90 ℃; for 40h; regioselective reaction; Inert atmosphere;

DOI:10.1021/jacs.6b06239

Reference yield: 74.5%

1,2-Dichloro-3-iodobenzene (2401-21-0) + bis(pinacol)diborane (73183-34-3) → 1,2-dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)benzene (1255760-30-5)

Guidance literature:

With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 20 - 85 ℃; for 4.66667h;

Reference yield: 91.1%

1,2-dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)benzene (1255760-30-5) + C29H17BrO → C35H20Cl2O

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide; In tetrahydrofuran; water; for 6h;

upstream raw materials:

1,2-Dichloro-3-iodobenzene

bis(pinacol)diborane

1,2-dichloro-benzene