ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate

Base Information

• Chemical Name: ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate
• CAS No.: 1456904-99-6
• Molecular Formula: C₂₅H₂₂N₂O₅
• Molecular Weight: 430.46

Synonyms:ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate

Chemical Property of ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate

There total 5 articles about ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(3,4-dihydro-1H-isoquinolin-2-yl)-acetic acid ethyl ester (88014-09-9) + 1-((4-methoxyphenyl)methyl)-1H-pyrrole-2,5-dione (140480-96-2) → ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate (1456904-99-6)

Guidance literature:

With N-Bromosuccinimide; C₈₀H₆₈B₃F₆I₂N₁₃O₄; oxygen; In dichloromethane; at 20 ℃; for 1.5h; Reagent/catalyst; Irradiation;

DOI:10.1039/c4ra03631j

Reference yield: 72.0%

→ ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate (1456904-99-6)

Guidance literature:

With oxygen; copper(I) bromide; In acetonitrile; at 60 ℃; for 10h;

Reference yield: 51.0%

(3,4-dihydro-1H-isoquinolin-2-yl)-acetic acid ethyl ester (88014-09-9) + 1-[(4-methoxyphenyl)methyl]-2,5-pyrrolidinedione (108640-66-0) → ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate (1456904-99-6)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 2h; UV-irradiation;

DOI:10.1039/c3cc44486d

upstream raw materials:

4-methoxy-benzylamine

(3,4-dihydro-1H-isoquinolin-2-yl)-acetic acid ethyl ester

1-[(4-methoxyphenyl)methyl]-2,5-pyrrolidinedione

1,2,3,4-tetrahydroisoquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1456904-99-6 ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send